Model-Informed Drug Development (MIDD)

Quantitative Decision Making

Our cutting-edge Model-Informed Drug Development (MIDD) consulting service is revolutionizing the way biopharma companies approach the drug development process. MIDD is a powerful approach that leverages quantitative modeling and simulation to inform key decisions at every stage of drug development, from early discovery to regulatory approval. Key features of our MIDD Consulting service offering includes:

Strategic Guidance: Our team of MIDD experts collaborates with pharmaceutical companies, biotech firms, and research organizations to develop comprehensive MIDD strategies aligned with your drug development objectives. We help you make informed decisions and maximize the potential of your molecules.

Early-Phase Support: We specialize in optimizing early-phase clinical trial designs. By integrating MIDD principles, we enhance the probability of success in Phase I and II trials, leading to efficient dose selection and go/no-go decisions.

Population Pharmacokinetics and Pharmacodynamics: Our consultants excel in population pharmacokinetics (PopPK) and pharmacodynamics (PopPD) modeling. We evaluate drug exposure, variability, and responses across diverse patient populations, enabling personalized medicine approaches and dose individualization.

Dose Optimization: Through extensive modeling and simulation, we identify optimal dosing regimens for your compounds. This minimizes risks, maximizes therapeutic benefits, and accelerates the path to market.

Clinical Trial Design: Our consultants use clinical trial simulation to design efficient and informative clinical trials. By evaluating multiple potential clinical trial scenarios, facilitates robust data generation, and provides your study with the best chance of success.

Safety and Efficacy Assessment: Performing exposure-response analyses between drug exposures and corresponding safety or efficacy endpoints provides clarity on what is driving the respective signal.

Regulatory Interactions: We provide support in interactions with regulatory agencies, assisting in the preparation and submission of documents such as INDs, NDAs, and BLAs. Our expertise ensures compliance with regulatory expectations and facilitates successful approvals.

Real-World Data Integration: Our MIDD approach extends beyond clinical trials. We help you leverage real-world data to inform decision-making, enhance market access strategies, and support post-marketing efforts.

Cross-Therapeutic Expertise: Our team spans diverse therapeutic areas, including oncology, neuroscience, immunology, and more. This breadth allows us to tailor MIDD solutions to your specific drug development needs.

Our MIDD consulting service empowers you to harness the full potential of quantitative modeling and simulation in drug development. By adopting MIDD principles, you gain a competitive edge, make data-driven decisions, reduce development risks, and ultimately bring safer and more effective therapies to patients. Momentum Metrix is your ticket to embark on a transformative journey in Model-Informed Drug Development.


Interested in learning more about Momentum Metrix’s Model-Informed Drug Development capabilities, contact us at information@momentummetrix.com.