Dose Selection

The Fundamental Pillar of Effective Treatment

Selecting the right dose is pivotal in ensuring the safety and efficacy of your molecules. Getting the dose wrong is often cited as one of the primary reasons for failed drug development.

Key Features

Here’s why Momentum Metrix experience stands out in your dose selection strategy:

  1. Scientific Expertise: Our team of pharmacometricians brings unparalleled expertise to dose selection. We combine scientific rigor with extensive industry experience to guide your study’s dose selection effectively.

  2. Personalized Approach: We work closely with your team to tailor our dose selection strategies to your specific molecule and therapeutic area based upon prior exposures. Our goal is to help you make informed decisions that align with your drug development objectives.

  3. Quantitative Modeling: Leveraging advanced pharmacometric modeling and simulation, we provide quantitative insights into dose-exposure-response relationships. Our modeling allows for precise dose selection, optimizing therapeutic effects while minimizing risks.

  4. Early-Phase Guidance: Our consultants specialize in dose selection for early-phase clinical trials. We assist in designing dose escalation trials, conducting model-based simulations, to optimize dosing regimen selection for Phase I and II studies.

  5. Population Pharmacokinetics: We excel in population pharmacokinetics modeling, enabling us to understand variability in drug exposure across diverse populations. This knowledge informs dose individualization and personalized medicine approaches.

  6. Risk Mitigation: We identify potential safety concerns and adverse effects associated with different dose levels, helping you implement risk mitigation strategies to ensure patient safety.

  7. Regulatory Compliance: Our dose selection strategies align with regulatory expectations, facilitating efficient interactions with regulatory agencies and supporting successful submissions.

  8. Efficiency and Cost Savings: Model-guided dose selection minimizes the need for additional studies, reducing development costs and timelines. Our service is an investment in efficient drug development.

  9. Cross-Therapeutic Expertise: Our team spans diverse therapeutic areas, from oncology to neurology, enabling us to tailor dose selection strategies to meet the unique needs of your compound.

By choosing Momentum Metrix, you gain a strategic partner dedicated to optimizing your study’s dose selection. Our commitment to excellence ensures you make data-driven decisions that advance your drug development with confidence. Discover the difference that model-guided dose selection can make in your journey toward drug approval. Choose Momentum Metrix for a dose selection strategy that sets you on the path to success.


Interested in learning more about Momentum Metrix’s dose selection capabilities, contact us at information@momentummetrix.com.